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Name: ZHONG Jin
Title: Associate Professor; Co-chair of Technology Development and Transfer Committee
Dept.: State Key Laboratory of Microbial Resources
Tel: +86-10-64807401
Fax: +86-10-64807401
E-mail: zhongj@im.ac.cn
Add.: NO.1 West Beichen Road, Chaoyang District, Beijing 100101, P.R.China
Background:

Dr. Zhong got her BSc and MSc in Anhui Agricultural University. She graduated from College of Life Sciences of Peking University and received her Ph.D. degree in 2003. Then she joined the Institute of Microbiology, Chinese Academy of Sciences and now is the Associate Professor of State Key Laboratory of Microbial Resources of IM-CAS.


Research interests:

Dr. Zhong’s research concentrates on molecular genetics of Lactic Acid Bacteria (LAB), especially on the biosynthesis, genetic regulation, structural-function analysis and the application of the bioactive substances produced by LAB.

Awards & Honors:

2002   Second Prize of Science and Technology Progress of Anhui Province


Selected Publications and Books:

[1] Lin Y, Teng K, Huan L, Zhong J *. 2010. Dissection of the bridging pattern of bovicin HJ50, a lantibiotic containing a characteristic disulfide bridge. Microbiological Research  (in press) (doi:10.1016/j.micres. 2010.05.001)  

[2] Zhang Q, Zhong J*, Huan L*. 2010. Expression of Hepatitis B Virus surface antigen determinants in Lactococcus lactis for oral vaccination. Microbiological Research  (in press) ( doi:10.1016/j.micres.2010.02.002)

[3] Zhang Q, Zhong J*, Liang X, Liu W, Huan L*. 2010. Improvement of human interferon alpha secretion by Lactococcus lactis. Biotechnology Letters (in press) (doi: 10.1007/s10529-010-0285-x)

[4] Wu S, Feng C, Zhong J*, Huan L*. 2010. Enhanced production of recombinant Nattokinase in Bacillus subtilis by promoter optimization. World Journal of Microbiology and Biotechnology (in press)(doi: 10.1007/s11274-010-0432-5)

[5] Sun Z, Zhong J*, Liang X, Liu J, Chen X, Huan L*. 2009. Novel mechanism for nisin resistance via proteolytic degradation of nisin by nisin resistance protein (NSR). Antimicrobial Agents and Chemotherapy, 53:1964-1973.

[6] Liu G, Zhong J*, Ni J, Chen M, Xiao H, Huan L*. 2009. Characteristics of bovicin HJ50 gene cluster in Streptococcus bovis HJ50. Microbiology-SGM, 155, 584-593.

[7] Liang X, Sun Z, Zhong J*, Zhang Q, Huan L*. 2009. Adverse effect of nisin resistance protein on nisin-induced expression system in Lactococcus lactis. Microbiological Research  (doi:10.1016/j.micres.2009.10.001)

[8] Wu S, Feng C, Zhong J*, Huan L*. 2007. Roles of S3 site residues of Nattokinase on its activity and substrate specificity. Journal of Biochemistry 142: 357-364.

[9] Liang X, Zhong J*, Huan L*. 2007. Secretory expression of a heterologous Nattokinase in Lactococcus lactis. Applied Microbiology and Biotechnology 75:95-101.

[10] Liang X, Jia S, Sun Y, Chen M, Chen X, Zhong J*, Huan L*. 2007. Secretory expression of Nattokinase from Bacillus subtilis YF38 in Escherichia coli. Molecular Biotechnology 37:187-194

[11] Wu S, Zhong J* and Huan L *. 2006. Genetics of subpeptin JM4-A and subpeptin JM4-B production by Bacillus subtilis JM4. Biochemical and Biophysical Research Communications. 344: 1147-1154.

[12] Wu S, Jia S, Sun D, Chen M, Chen X, Zhong J*, Huan L*. 2005. Purification and characterization of two novel antimicrobial peptides Subpeptin JM4-A and Subpeptin JM4-B produced by Bacillus subtilis JM4. Current Microbiology, 51, 292-296.

Institute Of Microbiology Chinese Academy of Sciences
NO.1 West Beichen Road, Chaoyang District, Beijing 100101, China Phone: 0086-10-64807462 Fax: 0086-10-64807468 Email: office@im.ac.cn